A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID:
MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 protein
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]; [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased activity of CYP1A2 protein; [Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA]
3,4,5,3',4'-pentachlorobiphenyl analog results in increased expression of CYP1A2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 protein
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]; [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP1A2 mRNA; [AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]; [aroclor 1260 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A2 mRNA; [MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA; [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA