GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a1 | increases expression | EXP | | 6480464 | CTD | 7H-dibenzo(c,g)carbazole results in increased expression of CYP1A1 mRNA | PMID:23639521 | Cyp1a1 | multiple interactions | EXP | | 6480464 | CTD | 7H-dibenzo(c,g)carbazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] | PMID:23639521 | Cyp1a1 | increases expression | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | 7H-dibenzo(c,g)carbazole results in increased expression of CYP1A1 mRNA | PMID:23639521 | Cyp1a1 | multiple interactions | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | 7H-dibenzo(c,g)carbazole promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Benzo(a)pyrene promotes the reaction [7H-dibenzo(c,g)carbazole results in increased expression of CYP1A1 mRNA]; CYP1A1 protein affects the metabolism of and results in increased activity of 7H-dibenzo(c,g)carbazole; CYP1A1 protein results in decreased susceptibility to [Benzo(a)pyrene co-treated with 7H-dibenzo(c,g)carbazole] | PMID:15534862 PMID:23639521 | |
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