GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a1 | affects binding | EXP | | 6480464 | CTD | epigallocatechin gallate binds to CYP1A1 protein | PMID:23010222 | Cyp1a1 | increases activity | EXP | | 6480464 | CTD | epigallocatechin gallate results in increased activity of CYP1A1 protein | PMID:15895106 | Cyp1a1 | decreases expression | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in decreased expression of CYP1A1 mRNA | PMID:20816778 | Cyp1a1 | multiple interactions | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate inhibits the reaction [[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; epigallocatechin gallate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] | PMID:11064004 PMID:14558788 | |
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