GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a1 | increases activity | ISO | Cyp1a1 (Mus musculus) | 6480464 | CTD | Arsenic results in increased activity of CYP1A1 protein | PMID:15337587 | Cyp1a1 | increases expression | ISO | Cyp1a1 (Mus musculus) | 6480464 | CTD | Arsenic results in increased expression of CYP1A1 mRNA | PMID:15337587 | Cyp1a1 | increases expression | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | Arsenic results in increased expression of CYP1A1 mRNA | PMID:26988683 | Cyp1a1 | multiple interactions | ISO | Cyp1a1 (Mus musculus) | 6480464 | CTD | Arsenic inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; Arsenic inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Arsenic inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Arsenic inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Arsenic promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Arsenic promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; Arsenic promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Arsenic promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Arsenic promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Arsenic promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Arsenic promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Arsenic promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] | PMID:15337587 | Cyp1a1 | multiple interactions | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | [[Industrial Waste results in increased abundance of Trace Elements] which results in increased abundance of Arsenic] which affects the expression of CYP1A1 mRNA; [Benzo(a)pyrene co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of CYP1A1 protein; [Estradiol co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of CYP1A1 mRNA | PMID:32062438 PMID:34083740 PMID:35747940 | |
Go Back to source page | Continue to Ontology report |