Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:16767
Term: 3,4-dichloroaniline
Definition: A dichloroaniline having the two chloro-substituents at the 3- and 4-positions.
Chemical ID: MESH:C014464
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1increases expressionISOCYP1A1 (Homo sapiens)6480464CTD3,4-dichloroaniline results in increased expression of CYP1A1 mRNA; 3,4-dichloroaniline results in increased expression of CYP1A1 proteinPMID:21784029 PMID:24172598
Go Back to source page   Continue to Ontology report