Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol inhibits the reaction [Estradiol results in decreased expression of CYP1A1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA]; [Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 protein]; [Estradiol co-treated with Progesterone] affects the expression of CYP1A1 mRNA; Estradiol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Estradiol promotes the reaction [Cadmium Chloride results in decreased expression of CYP1A1 mRNA]
Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; fulvestrant inhibits the reaction [Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]
4,17 beta-dihydroxy-4-androstene-3-one inhibits the reaction [Estradiol results in increased expression of CYP1A1 mRNA]; 6-prenylnaringenin inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]]; 6-prenylnaringenin inhibits the reaction [Estradiol results in decreased expression of CYP1A1 mRNA]; [CYP1A1 protein results in increased oxidation of Estradiol] which results in increased chemical synthesis of 2-hydroxyestradiol; [Estradiol co-treated with 6-formylindolo(3,2-b)carbazole] results in increased activity of CYP1A1 protein; [Estradiol co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of CYP1A1 mRNA; [Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 mRNA]; [Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 protein]; [Estradiol co-treated with Tetrachlorodibenzodioxin] promotes the reaction [ESR1 protein binds to CYP1A1 enhancer]; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1A1 mRNA; [Estradiol co-treated with TGFB1 protein] results in decreased expression of CYP1A1 mRNA; [Estradiol co-treated with triclocarban] results in increased expression of CYP1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with Estradiol] promotes the reaction [ESR1 protein binds to CYP1A1 enhancer]; [Tetrachlorodibenzodioxin co-treated with Estradiol] promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; [Tetrachlorodibenzodioxin co-treated with Estradiol] results in increased expression of CYP1A1 mRNA; AHR mutant form inhibits the reaction [[Estradiol co-treated with triclocarban] results in increased expression of CYP1A1 mRNA]; Benzo(a)pyrene affects the reaction [CYP1A1 protein results in increased hydroxylation of Estradiol]; Benzo(a)pyrene promotes the reaction [Estradiol results in increased expression of CYP1A1 mRNA]; benzo(k)fluoranthene affects the reaction [CYP1A1 protein results in increased hydroxylation of Estradiol]; ESR1 mutant form inhibits the reaction [[Estradiol co-treated with triclocarban] results in increased expression of CYP1A1 mRNA]; Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Estradiol promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1A1 promoter]]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1A1 promoter]]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [SP1 protein binds to CYP1A1 promoter]]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1A1 protein]; NFIC protein inhibits the reaction [Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]; Plant Extracts inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]]; Plant Extracts inhibits the reaction [Estradiol results in decreased expression of CYP1A1 mRNA]; Resveratrol inhibits the reaction [CYP1A1 protein affects the metabolism of Estradiol]; Tamoxifen inhibits the reaction [Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]; Tamoxifen inhibits the reaction [Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]]; Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in decreased expression of CYP1A1 mRNA]
