GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp17a1 | affects expression | ISO | Cyp17a1 (Mus musculus) | 6480464 | CTD | Valproic Acid affects the expression of CYP17A1 mRNA | PMID:17292431 | Cyp17a1 | decreases expression | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | Valproic Acid results in decreased expression of CYP17A1 mRNA | PMID:19566492 PMID:37505509 | Cyp17a1 | increases expression | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | Valproic Acid results in increased expression of CYP17A1 mRNA; Valproic Acid results in increased expression of CYP17A1 protein | PMID:14576182 | Cyp17a1 | multiple interactions | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA] | PMID:20726872 | |
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