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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2456
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp17a1
Name: cytochrome P450, family 17, subfamily a, polypeptide 1
Acc ID: CHEBI:35033
Term: triphenyl phosphate
Definition: An aryl phosphate resulting from the formal condensation of phosphoric acid with 3 mol eq. of phenol.
Chemical ID: MESH:C005445
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp17a1decreases expressionISOCyp17a1 (Mus musculus)6480464CTDtriphenyl phosphate results in decreased expression of CYP17A1 mRNAPMID:26049154 PMID:26183808
Cyp17a1multiple interactionsISOCYP17A1 (Homo sapiens)6480464CTDtriphenyl phosphate inhibits the reaction [CGB3 protein results in increased expression of CYP17A1 mRNA]PMID:26049154
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