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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2451
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cycs
Name: cytochrome c, somatic
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cycsaffects localizationEXP 6480464CTDLipopolysaccharides affects the localization of CYCS proteinPMID:23200736
Cycsmultiple interactionsEXP 6480464CTDtigecycline inhibits the reaction [Lipopolysaccharides affects the localization of CYCS protein]PMID:23200736
Cycsincreases expressionISOCYCS (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of CYCS proteinPMID:20166893
Cycsmultiple interactionsISOCycs (Mus musculus)6480464CTD[Galactosamine co-treated with Lipopolysaccharides] results in increased localization of CYCS protein; [Lipopolysaccharides co-treated with Galactosamine] affects the localization of CYCS protein; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] affects the localization of CYCS protein]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased localization of CYCS protein]PMID:20558151 PMID:20850421
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