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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2398
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cpt2
Name: carnitine palmitoyltransferase 2
Acc ID: CHEBI:5001
Term: fenofibrate
Definition: A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Chemical ID: MESH:D011345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cpt2decreases expressionEXP 6480464CTDFenofibrate results in decreased expression of CPT2 proteinPMID:20118634
Cpt2increases expressionEXP 6480464CTDFenofibrate results in increased expression of CPT2 mRNAPMID:16595124 PMID:16707586 PMID:19395589 PMID:27665778 PMID:32741897
Cpt2increases expressionISOCPT2 (Homo sapiens)6480464CTDFenofibrate results in increased expression of CPT2 mRNAPMID:25572481
Cpt2multiple interactionsISOCpt2 (Mus musculus)6480464CTDFenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA]PMID:28871336
Cpt2multiple interactionsISOCPT2 (Homo sapiens)6480464CTD[Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNAPMID:24534255
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