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GENE - TERM ANNOTATION REPORT

RGD ID: 2379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Comt
Name: catechol-O-methyltransferase
Acc ID: DOID:1612
Term: breast cancer
Definition: A thoracic cancer that originates in the mammary gland. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Breast_cancer "DO" "DO", http://en.wikipedia.org/wiki/Mammary "DO" "DO", http://www.cancer.gov/cancertopics/types/breast "DO" "DO", http://www.nlm.nih.gov/medlineplus/breastcancer.html "DO" "DO", https://www.genome.gov/Genetic-Disorders/Breast-Cancer "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Comt ISOCOMT (Homo sapiens)2289712RGDmRNA:increased expression:breast 
Comtdisease_progressionISOCOMT (Homo sapiens)2289715RGDDNA:polymorphism: :p.V158M 
Comtno_associationISOCOMT (Homo sapiens)2289721RGDDNA:polymorphism: :p.V158M 
ComtsusceptibilityISOCOMT (Homo sapiens)2289710RGDDNA:polymorphism: :p.V158M 
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