GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Comt | increases methylation | EXP | | 6480464 | CTD | COMT protein results in increased methylation of catechol | PMID:11160877 | Comt | increases methylation | ISO | COMT (Homo sapiens) | 6480464 | CTD | COMT protein results in increased methylation of catechol | PMID:11160877 | Comt | increases response to substance | ISO | COMT (Homo sapiens) | 6480464 | CTD | COMT mutant form results in increased susceptibility to catechol | PMID:24141029 | Comt | multiple interactions | ISO | COMT (Homo sapiens) | 6480464 | CTD | COMT mutant form inhibits the reaction [[catechol co-treated with Hemin] results in increased expression of ALAS2 mRNA]; COMT mutant form inhibits the reaction [[catechol co-treated with Hemin] results in increased expression of HBB mRNA]; COMT mutant form inhibits the reaction [[catechol co-treated with Hemin] results in increased expression of HMBS mRNA]; COMT mutant form inhibits the reaction [catechol results in increased abundance of Guaiacol] | PMID:24141029 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |