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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2329
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cebpe
Name: CCAAT/enhancer binding protein epsilon
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpemultiple interactionsISOCEBPE (Homo sapiens)6480464CTD[Tretinoin co-treated with Arsenic Trioxide co-treated with Butyrates] results in increased expression of CEBPE mRNA; [Tretinoin co-treated with Arsenic Trioxide co-treated with hexamethylene bisacetamide] results in increased expression of CEBPE mRNA; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CEBPE mRNA; Arsenic Trioxide inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]PMID:12130515 PMID:16184197
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