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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2327
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cebpb
Name: CCAAT/enhancer binding protein beta
Acc ID: CHEBI:16118
Term: berberine
Definition: A botanical anti-fungal agent that has formula C20H18NO4.
Chemical ID: MESH:D001599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpbaffects phosphorylationISOCebpb (Mus musculus)6480464CTDBerberine affects the phosphorylation of CEBPB proteinPMID:28038998
Cebpbaffects phosphorylationISOCEBPB (Homo sapiens)6480464CTDBerberine affects the phosphorylation of CEBPB proteinPMID:28038998
Cebpbincreases expressionISOCEBPB (Homo sapiens)6480464CTDBerberine results in increased expression of CEBPB mRNAPMID:28038998
Cebpbmultiple interactionsISOCEBPB (Homo sapiens)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Berberine results in increased phosphorylation of CEBPB protein]; CEBPB protein promotes the reaction [Berberine results in increased expression of CD36 mRNA]PMID:28038998
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