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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2326
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cebpa
Name: CCAAT/enhancer binding protein alpha
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpadecreases expressionISOCebpa (Mus musculus)6480464CTDArsenic Trioxide results in decreased expression of CEBPA proteinPMID:15916724
Cebpadecreases expressionISOCEBPA (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of CEBPA mRNA; Arsenic Trioxide results in decreased expression of CEBPA proteinPMID:19662097 PMID:21257625
Cebpaincreases expressionISOCEBPA (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of CEBPA mRNAPMID:20458559
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