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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2280
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cav1
Name: caveolin 1
Acc ID: CHEBI:35807
Term: N-nitrosodimethylamine
Definition: A nitrosamine that has formula C2H6N2O.
Chemical ID: MESH:D004128
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cav1increases expressionEXP 6480464CTDDimethylnitrosamine results in increased expression of CAV1 mRNA; Dimethylnitrosamine results in increased expression of CAV1 proteinPMID:18364076 PMID:25380136
Cav1multiple interactionsEXP 6480464CTDDimethylnitrosamine promotes the reaction [CAV1 protein binds to NOS3 protein]PMID:18364076
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