GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cav1 | multiple interactions | EXP | | 6480464 | CTD | [Semaxinib co-treated with Oxygen deficiency] results in decreased expression of CAV1 mRNA; [Semaxinib co-treated with Oxygen deficiency] results in decreased expression of CAV1 protein; Simvastatin inhibits the reaction [[Semaxinib co-treated with Oxygen deficiency] results in decreased expression of CAV1 protein] | PMID:16698853 PMID:24835767 | Cav1 | increases expression | ISO | CAV1 (Homo sapiens) | 6480464 | CTD | Oxygen deficiency results in increased expression of CAV1 mRNA; Oxygen deficiency results in increased expression of CAV1 protein | PMID:18717816 | Cav1 | increases response to substance | ISO | Cav1 (Mus musculus) | 6480464 | CTD | CAV1 gene mutant form results in increased susceptibility to Oxygen deficiency | PMID:24835767 | Cav1 | multiple interactions | ISO | Cav1 (Mus musculus) | 6480464 | CTD | [CAV1 gene mutant form results in increased susceptibility to Oxygen deficiency] which results in increased expression of CYBB mRNA; [CAV1 gene mutant form results in increased susceptibility to Oxygen deficiency] which results in increased expression of CYBB protein; [CAV1 gene mutant form results in increased susceptibility to Oxygen deficiency] which results in increased expression of NOX4 mRNA; [CAV1 gene mutant form results in increased susceptibility to Oxygen deficiency] which results in increased expression of NOX4 protein | PMID:24835767 | Cav1 | multiple interactions | ISO | CAV1 (Homo sapiens) | 6480464 | CTD | [Oxygen deficiency co-treated with 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene] results in increased expression of CAV1 protein; N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Oxygen deficiency results in increased expression of CAV1 protein] | PMID:18717816 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |