GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | multiple interactions | EXP | | 6480464 | CTD | [candesartan co-treated with epigallocatechin gallate] inhibits the reaction [Gentamicins results in increased expression of CASP3 protein]; [epigallocatechin gallate co-treated with coenzyme Q10] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; epigallocatechin gallate inhibits the reaction [Acrylamide results in increased activity of CASP3 protein]; epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of CASP3 protein]; epigallocatechin gallate inhibits the reaction [Gentamicins results in increased expression of CASP3 protein]; epigallocatechin gallate inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; epigallocatechin gallate promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CASP3 protein]] | PMID:17936647 PMID:27920337 PMID:28056603 PMID:29999212 PMID:30368989 PMID:33393703 | Casp3 | affects cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate affects the cleavage of CASP3 protein | PMID:15975156 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in increased activity of CASP3 protein | PMID:15657356 PMID:15705601 PMID:15764647 | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate analog results in increased cleavage of CASP3 protein; epigallocatechin gallate results in increased cleavage of CASP3 protein | PMID:16115949 PMID:22348037 | Casp3 | increases expression | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | epigallocatechin gallate results in increased expression of CASP3 protein | PMID:32512070 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | epigallocatechin gallate inhibits the reaction [Formaldehyde results in increased expression of CASP3 protein]; epigallocatechin gallate inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]; epigallocatechin gallate inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; epigallocatechin gallate results in increased expression of and results in increased cleavage of CASP3 protein | PMID:28365685 PMID:30395894 PMID:34600025 PMID:36056792 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | [arsenic trioxide co-treated with epigallocatechin gallate] results in increased activity of CASP3 protein; epigallocatechin gallate inhibits the reaction [Hydrogen Peroxide results in increased cleavage of and results in increased activity of CASP3 protein]; epigallocatechin gallate inhibits the reaction [Nitroprusside binds to and results in increased activity of CASP3 protein]; epigallocatechin gallate inhibits the reaction [potassium chromate(VI) results in increased cleavage of and results in increased activity of CASP3 protein] | PMID:12672908 PMID:15795422 PMID:20950636 PMID:22079256 PMID:23665936 | | ||||||||||||||||||||||
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