GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases activity | EXP | | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased activity of CASP3 protein | PMID:16337876 PMID:20114059 PMID:21187080 PMID:24291486 | Casp3 | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein] | PMID:20114059 PMID:24291486 | Casp3 | increases activity | ISO | Casp3 (Mus musculus) | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased activity of CASP3 protein | PMID:17263905 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased activity of CASP3 protein | PMID:11488593 PMID:19326901 | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased cleavage of CASP3 protein | PMID:24825450 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased cleavage of and results in increased activity of CASP3 protein; pyrazolanthrone inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein] | PMID:16322078 | | ||||||||||||||||||||||
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