GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | 2-Methoxyestradiol results in increased cleavage of CASP3 protein | PMID:26011145 | Casp3 | increases expression | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | 2-Methoxyestradiol results in increased expression of CASP3 protein modified form | PMID:23967052 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | 2-Methoxyestradiol promotes the reaction [Quercetin results in increased cleavage of CASP3 protein]; Arsenic Trioxide promotes the reaction [2-Methoxyestradiol results in increased expression of CASP3 protein modified form]; Quercetin promotes the reaction [2-Methoxyestradiol results in increased cleavage of CASP3 protein] | PMID:23967052 PMID:26011145 | | ||||||||||||||||||||||
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