GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases expression | EXP | | 6480464 | CTD | Benzene results in increased expression of CASP3 mRNA | PMID:21143203 | Casp3 | multiple interactions | EXP | | 6480464 | CTD | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of CASP3 mRNA; Decitabine inhibits the reaction [Benzene results in increased expression of CASP3 mRNA] | PMID:17905399 PMID:21143203 | Casp3 | increases activity | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Benzene results in increased activity of CASP3 protein | PMID:27339418 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Benzene analog results in increased activity of CASP3 protein | PMID:15826604 | Casp3 | increases expression | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Benzene results in increased expression of CASP3 mRNA | PMID:36306860 | Casp3 | increases expression | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Benzene results in increased expression of CASP3 mRNA | PMID:19162166 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | [Benzene co-treated with Formaldehyde] results in increased activity of CASP3 protein; shikonin inhibits the reaction [Benzene results in increased expression of CASP3 mRNA] | PMID:27339418 PMID:36306860 | |
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