GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cacna1c | decreases expression | EXP | | 6480464 | CTD | Verapamil results in decreased expression of CACNA1C mRNA; Verapamil results in decreased expression of CACNA1C protein | PMID:19791473 | Cacna1c | multiple interactions | EXP | | 6480464 | CTD | Mevalonic Acid inhibits the reaction [Verapamil results in decreased expression of CACNA1C mRNA]; Mevalonic Acid inhibits the reaction [Verapamil results in decreased expression of CACNA1C protein] | PMID:19791473 | Cacna1c | increases response to substance | ISO | CACNA1C (Homo sapiens) | 6480464 | CTD | CACNA1C gene polymorphism results in increased susceptibility to Verapamil | PMID:20031608 | Cacna1c | multiple interactions | ISO | Cacna1c (Mus musculus) | 6480464 | CTD | Verapamil inhibits the reaction [Iron-Dextran Complex affects the expression of CACNA1C protein] | PMID:27095094 | |
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