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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2225
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Btg2
Name: BTG anti-proliferation factor 2
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Btg2increases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of BTG2 mRNAPMID:19638242 PMID:21813463
Btg2multiple interactionsEXP 6480464CTDDiethylnitrosamine affects the localization of and results in increased expression of BTG2 proteinPMID:19254457
Btg2decreases expressionISOBtg2 (Mus musculus)6480464CTDDiethylnitrosamine results in decreased expression of BTG2 mRNAPMID:18393292
Btg2decreases response to substanceISOBtg2 (Mus musculus)6480464CTDBTG2 protein results in decreased susceptibility to DiethylnitrosaminePMID:18393292
Btg2increases expressionISOBtg2 (Mus musculus)6480464CTDDiethylnitrosamine results in increased expression of BTG2 mRNAPMID:19100860 PMID:21607683 PMID:24535843
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