GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bdnf | decreases acetylation | EXP | | 6480464 | CTD | Dexamethasone results in decreased acetylation of BDNF exon | PMID:31518422 | Bdnf | decreases expression | EXP | | 6480464 | CTD | Dexamethasone results in decreased expression of BDNF mRNA; Dexamethasone results in decreased expression of BDNF protein | PMID:29111458 PMID:31518422 | Bdnf | multiple interactions | EXP | | 6480464 | CTD | BDNF protein inhibits the reaction [Dexamethasone results in decreased expression of SLC17A7 mRNA]; BDNF protein inhibits the reaction [Dexamethasone results in decreased expression of SLC1A1 mRNA]; BDNF protein inhibits the reaction [Dexamethasone results in increased expression of GAD1 mRNA]; Dexamethasone inhibits the reaction [Arsanilic Acid results in decreased expression of BDNF mRNA]; Dexamethasone inhibits the reaction [Arsanilic Acid results in decreased expression of BDNF protein]; Dexamethasone promotes the reaction [HDAC2 protein binds to BDNF promoter]; Dexamethasone promotes the reaction [NR3C1 protein binds to BDNF promoter]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Arsanilic Acid results in decreased expression of BDNF mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Arsanilic Acid results in decreased expression of BDNF protein]]; Mifepristone inhibits the reaction [Dexamethasone results in decreased acetylation of BDNF exon]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of BDNF mRNA]; romidepsin inhibits the reaction [Dexamethasone results in decreased acetylation of BDNF exon]; romidepsin inhibits the reaction [Dexamethasone results in decreased expression of BDNF mRNA] | PMID:30628712 PMID:31518422 | Bdnf | decreases expression | ISO | BDNF (Homo sapiens) | 6480464 | CTD | Dexamethasone results in decreased expression of BDNF mRNA; Dexamethasone results in decreased expression of BDNF protein | PMID:15215491 PMID:25047013 | |
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