GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl2l1 | affects expression | EXP | | 6480464 | CTD | Arsenic Trioxide affects the expression of BCL2L1 protein | PMID:23337567 | Bcl2l1 | decreases expression | EXP | | 6480464 | CTD | Arsenic Trioxide results in decreased expression of BCL2L1 mRNA; Arsenic Trioxide results in decreased expression of BCL2L1 protein | PMID:19730151 PMID:23201927 PMID:28391263 | Bcl2l1 | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvianolic acid B inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]]; salvianolic acid A inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; salvianolic acid B inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein] | PMID:23201927 PMID:28391263 | Bcl2l1 | affects expression | ISO | BCL2L1 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide affects the expression of BCL2L1 protein | PMID:23770046 | Bcl2l1 | affects response to substance | ISO | BCL2L1 (Homo sapiens) | 6480464 | CTD | BCL2L1 protein affects the susceptibility to Arsenic Trioxide | PMID:10648417 PMID:11468182 | Bcl2l1 | decreases expression | ISO | Bcl2l1 (Mus musculus) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of BCL2L1 mRNA; Arsenic Trioxide results in decreased expression of BCL2L1 protein | PMID:28454374 PMID:28587418 | Bcl2l1 | decreases expression | ISO | BCL2L1 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of BCL2L1 mRNA; Arsenic Trioxide results in decreased expression of BCL2L1 protein | PMID:11739184 PMID:12480548 PMID:15142122 PMID:15665116 PMID:16105982 PMID:16360329 PMID:18349030 PMID:18546268 PMID:19763917 PMID:21889928 PMID:23337567 PMID:23861973 PMID:24466103 PMID:24944602 PMID:24956101 PMID:25335113 PMID:25416439 PMID:27561292 PMID:29738779 PMID:30472098 PMID:34413873 | Bcl2l1 | increases expression | ISO | BCL2L1 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased expression of BCL2L1 mRNA; Arsenic Trioxide results in increased expression of BCL2L1 protein | PMID:17530438 PMID:23082001 | Bcl2l1 | multiple interactions | ISO | Bcl2l1 (Mus musculus) | 6480464 | CTD | [Genistein co-treated with Arsenic Trioxide] results in decreased expression of BCL2L1 protein; Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in decreased expression of BCL2L1 protein]; Drugs, Chinese Herbal promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein] | PMID:21078540 PMID:28587418 | Bcl2l1 | multiple interactions | ISO | BCL2L1 (Homo sapiens) | 6480464 | CTD | [Arsenic Trioxide co-treated with epigallocatechin gallate] results in decreased expression of BCL2L1 protein; [Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased expression of BCL2L1 protein; [Arsenic Trioxide co-treated with IL24 protein] results in decreased expression of BCL2L1; [Arsenic Trioxide co-treated with Quercetin] results in decreased expression of BCL2L1 protein; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of BCL2L1 mRNA; [Genistein co-treated with Arsenic Trioxide] results in decreased expression of BCL2L1 protein; [paricalcitol co-treated with Arsenic Trioxide] results in decreased expression of BCL2L1; [Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein; Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; allicin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; Genistein promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; Hydrogen Peroxide inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; MAPK8 affects the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; MMP9 protein inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; Wortmannin inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2L1 protein]] | PMID:12883035 PMID:15142122 PMID:15781666 PMID:18281123 PMID:18359480 PMID:18546268 PMID:20950636 PMID:21078540 PMID:23082001 PMID:24956101 PMID:27561292 PMID:32645343 | |
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