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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2200
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l1
Name: Bcl2-like 1
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l1multiple interactionsEXP 6480464CTD[6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide co-treated with [Potassium Dichromate results in increased abundance of chromium hexavalent ion]] results in decreased expression of BCL2L1 protein; [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of BCL2L1 proteinPMID:35307491
Bcl2l1decreases expressionISOBCL2L1 (Homo sapiens)6480464CTDchromium hexavalent ion results in decreased expression of BCL2L1 proteinPMID:16166740
Bcl2l1increases expressionISOBCL2L1 (Homo sapiens)6480464CTDchromium hexavalent ion results in increased expression of BCL2L1 proteinPMID:25448439 PMID:29069462
Bcl2l1multiple interactionsISOBCL2L1 (Homo sapiens)6480464CTDLuteolin inhibits the reaction [chromium hexavalent ion results in increased expression of BCL2L1 protein]; TP53 protein affects the reaction [chromium hexavalent ion results in decreased expression of BCL2L1 protein]PMID:16166740 PMID:25448439
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