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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2200
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l1
Name: Bcl2-like 1
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l1affects expressionEXP 6480464CTDCadmium affects the expression of BCL2L1 mRNA; Cadmium affects the expression of BCL2L1 proteinPMID:25388156
Bcl2l1increases expressionEXP 6480464CTDCadmium results in increased expression of BCL2L1 proteinPMID:25388156
Bcl2l1increases cleavageISOBCL2L1 (Homo sapiens)6480464CTDCadmium results in increased cleavage of BCL2L1 proteinPMID:10970901
Bcl2l1multiple interactionsISOBCL2L1 (Homo sapiens)6480464CTD[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with fenvalerate] results in increased expression of BCL2L1 protein; BCL2L1 protein inhibits the reaction [Cadmium affects the localization of DNASE2 protein]PMID:22677345 PMID:28949029
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