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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2200
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l1
Name: Bcl2-like 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l1multiple interactionsEXP 6480464CTDEstradiol inhibits the reaction [Dimethylnitrosamine results in decreased expression of BCL2L1 protein]PMID:14659978
Bcl2l1affects expressionISOBCL2L1 (Homo sapiens)6480464CTDEstradiol affects the expression of BCL2L1 mRNAPMID:11896290
Bcl2l1decreases expressionISOBCL2L1 (Homo sapiens)6480464CTDEstradiol analog results in decreased expression of BCL2L1 mRNA; Estradiol analog results in decreased expression of BCL2L1 protein; Estradiol results in decreased expression of BCL2L1 mRNAPMID:21632981 PMID:23373633 PMID:24758408 PMID:31614463 PMID:36460128
Bcl2l1increases expressionISOBCL2L1 (Homo sapiens)6480464CTDEstradiol results in increased expression of BCL2L1 mRNA; Estradiol results in increased expression of BCL2L1 proteinPMID:15969986 PMID:19698761 PMID:24481588
Bcl2l1multiple interactionsISOBCL2L1 (Homo sapiens)6480464CTDEGF protein promotes the reaction [Estradiol results in decreased expression of BCL2L1 mRNA]PMID:24758408
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