GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl2 | decreases expression | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | Flavonoids results in decreased expression of BCL2 mRNA; Flavonoids results in decreased expression of BCL2 protein | PMID:23063593 PMID:24036141 PMID:28811126 | Bcl2 | multiple interactions | ISO | Bcl2 (Mus musculus) | 6480464 | CTD | Flavonoids inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 mRNA] | PMID:23279844 | Bcl2 | multiple interactions | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | Flavonoids inhibits the reaction [AGT protein results in decreased expression of BCL2 mRNA]; Flavonoids inhibits the reaction [AGT protein results in decreased expression of BCL2 protein]; Flavonoids inhibits the reaction [BCL2 mutant form promotes the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]]; Flavonoids inhibits the reaction [BCL2 mutant form promotes the reaction [AGT protein results in increased expression of AGTRAP protein]]; Flavonoids inhibits the reaction [BCL2 mutant form promotes the reaction [AGT protein results in increased expression of BAX mRNA]]; Flavonoids inhibits the reaction [BCL2 mutant form promotes the reaction [AGT protein results in increased expression of CYBA mRNA]]; Flavonoids inhibits the reaction [BCL2 mutant form promotes the reaction [AGT protein results in increased expression of CYBA protein]] | PMID:23994555 | |
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