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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:53444
Term: potassium dichromate
Definition: A potassium salt that is the dipotassium salt of dichromic acid.
Chemical ID: MESH:D011192
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionEXP 6480464CTDPotassium Dichromate results in increased expression of BAX mRNA; Potassium Dichromate results in increased expression of BAX proteinPMID:18547707 PMID:21262251 PMID:25245570 PMID:26348139
Baxmultiple interactionsEXP 6480464CTD[Potassium Dichromate results in increased abundance of chromium hexavalent ion] promotes the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased expression of BAX protein]; [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of BAX mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAX protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAX protein]; Carvedilol inhibits the reaction [Potassium Dichromate results in increased expression of BAX protein]PMID:18547707 PMID:21262251 PMID:25245570 PMID:30974164 PMID:35307491 PMID:36849043
Baxincreases expressionISOBax (Mus musculus)6480464CTDPotassium Dichromate results in increased expression of BAX proteinPMID:19219935
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