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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:26776
Term: stilbenoid
Definition: Any olefinic compound characterised by a 1,2-diphenylethylene backbone.
Chemical ID: MESH:D013267
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxaffects localizationISOBAX (Homo sapiens)6480464CTDStilbenes analog affects the localization of BAX proteinPMID:18449500
Baxincreases expressionISOBAX (Homo sapiens)6480464CTD[Stilbenes results in increased expression of TP53 protein] which results in increased expression of BAX proteinPMID:23059970
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Stilbenes analog affects the localization of BAX protein]; SB 203580 inhibits the reaction [Stilbenes analog affects the localization of BAX protein]PMID:18449500
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