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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2172
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp1b3
Name: ATPase Na+/K+ transporting subunit beta 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp1b3affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of ATP1B3 mRNAPMID:22298810
Atp1b3decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of ATP1B3 mRNAPMID:33387578
Atp1b3increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of ATP1B3 mRNAPMID:16054898 PMID:34747641
Atp1b3affects expressionISOAtp1b3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ATP1B3 mRNAPMID:21570461
Atp1b3increases expressionISOAtp1b3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ATP1B3 mRNAPMID:17942748 PMID:23994337
Atp1b3multiple interactionsISOAtp1b3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATP1B3 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of ATP1B3 mRNAPMID:17942748 PMID:25975270
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