GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ar | increases expression | ISO | Ar (Mus musculus) | 6480464 | CTD | Prednisolone results in increased expression of AR mRNA; Prednisolone results in increased expression of AR protein | PMID:19490052 | Ar | multiple interactions | ISO | Ar (Mus musculus) | 6480464 | CTD | [Phenytoin co-treated with Prednisolone] results in increased expression of AR protein | PMID:19490052 | Ar | multiple interactions | ISO | AR (Homo sapiens) | 6480464 | CTD | Prednisolone binds to and results in decreased activity of AR protein; Prednisolone binds to and results in increased activity of AR protein; Prednisolone binds to and results in increased activity of AR protein mutant form | PMID:11956172 PMID:25752796 | |
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