GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ar | decreases expression | EXP | | 6480464 | CTD | Triclosan results in decreased expression of AR mRNA; Triclosan results in decreased expression of AR protein | PMID:19118620 | Ar | multiple interactions | EXP | | 6480464 | CTD | Triclosan inhibits the reaction [Testosterone binds to AR protein] | PMID:17992702 | Ar | multiple interactions | ISO | AR (Homo sapiens) | 6480464 | CTD | Triclosan binds to and results in decreased activity of AR protein; Triclosan binds to and results in increased activity of AR protein; Triclosan inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Triclosan inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Triclosan inhibits the reaction [Metribolone results in increased activity of AR protein]; Triclosan promotes the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein] | PMID:18324785 PMID:20943248 PMID:27436773 PMID:28728110 PMID:29427707 PMID:33049310 | |
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