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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2130
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apoa1
Name: apolipoprotein A1
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoa1affects bindingISOAPOA1 (Homo sapiens)6480464CTDAPOA1 protein binds to ZincPMID:23896426
Apoa1decreases expressionISOAPOA1 (Homo sapiens)6480464CTDZinc deficiency results in decreased expression of APOA1 mRNA; Zinc results in decreased expression of APOA1 proteinPMID:12107072 PMID:12679171
Apoa1increases expressionISOAPOA1 (Homo sapiens)6480464CTDZinc results in increased expression of APOA1 mRNAPMID:12107072
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