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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2118
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Anxa1
Name: annexin A1
Acc ID: CHEBI:65887
Term: eurycomanone
Definition: A quassinoid isolated from Eurycoma longifolia and has been shown to exhibit antineoplastic and antimalarial activties.
Chemical ID: MESH:C506425
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Anxa1decreases expressionISOANXA1 (Homo sapiens)6480464CTDeurycomanone results in decreased expression of ANXA1 mRNA; eurycomanone results in decreased expression of ANXA1 proteinPMID:21903368
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