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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2118
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Anxa1
Name: annexin A1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Anxa1increases expressionEXP 6480464CTDTretinoin results in increased expression of ANXA1 mRNAPMID:24977338
Anxa1decreases expressionISOANXA1 (Homo sapiens)6480464CTDTretinoin results in decreased expression of ANXA1 mRNA; Tretinoin results in decreased expression of ANXA1 proteinPMID:23830798 PMID:28886987
Anxa1increases expressionISOANXA1 (Homo sapiens)6480464CTDTretinoin results in increased expression of ANXA1 mRNAPMID:15982314 PMID:16140955 PMID:21934132 PMID:33167477
Anxa1multiple interactionsISOAnxa1 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of ANXA1 mRNA; [bisphenol F co-treated with Tretinoin] results in decreased expression of ANXA1 mRNA; [bisphenol S co-treated with Tretinoin] results in decreased expression of ANXA1 mRNAPMID:30951980
Anxa1multiple interactionsISOANXA1 (Homo sapiens)6480464CTDThiophenes analog promotes the reaction [Tretinoin results in increased expression of ANXA1 mRNA]PMID:16140955
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