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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2092
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1b1
Name: aldo-keto reductase family 1 member B1
Acc ID: CHEBI:41607
Term: crotonaldehyde
Definition: An enal consisting of propene having a formyl group at the 1-position.
Chemical ID: MESH:C012796
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b1increases reductionISOAKR1B1 (Homo sapiens)6480464CTDAKR1B1 protein results in increased reduction of 2-butenal; AKR1B1 protein results in increased reduction of 2-butenal metabolitePMID:21329684 PMID:9890881
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