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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2087
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh1a1
Name: aldehyde dehydrogenase 1 family, member A1
Acc ID: CHEBI:6636
Term: magnesium dichloride
Definition: A magnesium salt comprising of two chlorine atoms bound to a magnesium atom.
Chemical ID: MESH:D015636
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh1a1decreases activityEXP 6480464CTDMagnesium Chloride results in decreased activity of ALDH1A1 proteinPMID:10998257
Aldh1a1multiple interactionsEXP 6480464CTDMagnesium Chloride inhibits the reaction [ALDH1A1 protein affects the oxidation of 9-cis-retinal]; Magnesium Chloride inhibits the reaction [ALDH1A1 protein affects the oxidation of Retinaldehyde]PMID:17167544
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