GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | decreases phosphorylation | EXP | | 6480464 | CTD | Isoflurane results in decreased phosphorylation of AKT1 protein | PMID:25597859 | Akt1 | increases phosphorylation | EXP | | 6480464 | CTD | Isoflurane results in increased phosphorylation of AKT1 protein | PMID:16249675 | Akt1 | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]; IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]; MK 2206 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]; Sirolimus inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]; U 0126 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] | PMID:25597859 | Akt1 | decreases phosphorylation | ISO | Akt1 (Mus musculus) | 6480464 | CTD | Isoflurane results in decreased phosphorylation of AKT1 protein | PMID:34553399 | Akt1 | multiple interactions | ISO | Akt1 (Mus musculus) | 6480464 | CTD | fraxetin inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein] | PMID:34553399 | | ||||||||||||||||||||||
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