GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | increases phosphorylation | EXP | | 6480464 | CTD | Zinc Sulfate results in increased phosphorylation of AKT1 protein | PMID:20100827 | Akt1 | multiple interactions | EXP | | 6480464 | CTD | RTKI cpd inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]; tyrphostin AG 1024 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein] | PMID:19946718 PMID:20100827 | Akt1 | increases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Zinc Sulfate results in increased phosphorylation of AKT1 protein | PMID:15355987 PMID:19946718 | Akt1 | increases phosphorylation | ISO | Akt1 (Mus musculus) | 6480464 | CTD | Zinc Sulfate results in increased phosphorylation of AKT1 protein | PMID:16224792 | Akt1 | multiple interactions | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc Sulfate results in increased phosphorylation of and results in increased activity of AKT1 protein]; IGF1R mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of and results in increased activity of AKT1 protein]; Zinc Sulfate results in increased phosphorylation of and results in increased activity of AKT1 protein | PMID:15355987 PMID:16973122 PMID:19946718 | Akt1 | multiple interactions | ISO | Akt1 (Mus musculus) | 6480464 | CTD | wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein] | PMID:16224792 | |
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