Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
AHR protein affects the reaction [[indeno(1,2,3-cd)pyrene co-treated with Antigens, Dermatophagoides] results in increased expression of IRF4 mRNA]; AHR protein affects the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of BCL6 mRNA]]; AHR protein affects the reaction [indeno(1,2,3-cd)pyrene promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL21 mRNA]]
1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein]; 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [indeno(1,2,3-cd)pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene] promotes the reaction [pyrene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with pyrene] promotes the reaction [fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [chrysene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(k)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benzo(j)fluoranthene results in increased activity of AHR protein]; [benz(a)anthracene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; [Benzo(a)pyrene co-treated with benzo(j)fluoranthene co-treated with benzo(k)fluoranthene co-treated with chrysene co-treated with indeno(1,2,3-cd)pyrene co-treated with fluoranthene co-treated with pyrene] promotes the reaction [benz(a)anthracene results in increased activity of AHR protein]; [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein] which results in increased abundance of Kynurenine; AHR promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of IKZF1 protein]; AHR promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETV6 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MKI67 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MYC protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of RUNX1 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein]; indeno(1,2,3-cd)pyrene promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]; U 0126 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein]
