GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ahr | affects activity | ISO | Ahr (Mus musculus) | 6480464 | CTD | butylbenzyl phthalate affects the activity of AHR protein | PMID:18294747 | Ahr | affects localization | ISO | AHR (Homo sapiens) | 6480464 | CTD | butylbenzyl phthalate affects the localization of AHR protein | PMID:22138065 | Ahr | increases expression | ISO | AHR (Homo sapiens) | 6480464 | CTD | butylbenzyl phthalate results in increased expression of AHR mRNA; butylbenzyl phthalate results in increased expression of AHR protein | PMID:22138065 | Ahr | multiple interactions | ISO | AHR (Homo sapiens) | 6480464 | CTD | 3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of AHR mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of AHR protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]; butylbenzyl phthalate binds to and results in increased activity of AHR protein; butylbenzyl phthalate promotes the reaction [AHR protein binds to ARNT protein]; butylbenzyl phthalate promotes the reaction [AHR protein binds to CYP1B1 promoter] | PMID:22138065 PMID:23220035 | | ||||||||||||||||||||||
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