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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2070 Species: Rattus norvegicus RGD Object: Gene Symbol: Agtr1a Name: angiotensin II receptor, type 1a

Acc ID: CHEBI:50122 Term: rosiglitazone Definition: A thiazolidenedione that has formula C18H19N3O3S. CasRN: 122320-73-4 Chemical ID: MESH:C089730

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	rosiglitazone inhibits the reaction [AGT protein modified form results in decreased expression of AGTR1 protein] rosiglitazone inhibits the reaction [AGT protein modified form results in increased expression of AGTR1 protein]	PMID:16344371