GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agt | increases abundance | EXP | | 6480464 | CTD | [AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species; AGT protein modified form results in increased abundance of Reactive Oxygen Species; AGT protein results in increased abundance of Reactive Oxygen Species | PMID:15123525 PMID:16531806 PMID:16940222 PMID:18854758 PMID:19145780 PMID:22427991 PMID:24037962 | Agt | multiple interactions | EXP | | 6480464 | CTD | [AGT protein modified form results in increased abundance of Reactive Oxygen Species] which results in increased activity of TRPC6 protein; [Egtazic Acid co-treated with Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone] inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; acetovanillone inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Allopurinol inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Carvedilol inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Resveratrol inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Rotenone inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; SOD2 protein inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; theaflavin-3,3'-digallate inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; TXNIP protein promotes the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Zinc promotes the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] | PMID:15123525 PMID:15607907 PMID:15878161 PMID:16531806 PMID:16940222 PMID:18854758 PMID:19145780 PMID:22427991 PMID:24037962 PMID:35406003 | Agt | increases abundance | ISO | Agt (Mus musculus) | 6480464 | CTD | AGT protein modified form results in increased abundance of Reactive Oxygen Species | PMID:27099261 PMID:30703374 | Agt | increases abundance | ISO | AGT (Homo sapiens) | 6480464 | CTD | AGT protein modified form results in increased abundance of Reactive Oxygen Species; AGT protein results in increased abundance of Reactive Oxygen Species | PMID:18550065 PMID:20015842 PMID:23994555 PMID:28834606 PMID:30354818 | Agt | multiple interactions | ISO | Agt (Mus musculus) | 6480464 | CTD | [AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased abundance of Reactive Oxygen Species; [SIRT4 results in increased acetylation of and results in decreased activity of SOD2 protein] promotes the reaction [AGT protein modified form results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [AGT protein modified form results in increased abundance of Reactive Oxygen Species]; FNDC5 protein inhibits the reaction [AGT protein modified form results in increased abundance of Reactive Oxygen Species]; SIRT4 promotes the reaction [AGT protein modified form results in increased abundance of Reactive Oxygen Species] | PMID:17620961 PMID:27099261 PMID:30703374 | Agt | multiple interactions | ISO | AGT (Homo sapiens) | 6480464 | CTD | BCL2 mutant form promotes the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; candesartan inhibits the reaction [AGT protein results in increased chemical synthesis of Reactive Oxygen Species]; Flavonoids inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Flavonoids inhibits the reaction [BCL2 mutant form promotes the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]]; Niacin inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Plant Extracts inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Plant Extracts inhibits the reaction [BCL2 mutant form promotes the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]]; SFRP5 protein inhibits the reaction [AGT protein modified form results in increased abundance of Reactive Oxygen Species] | PMID:18550065 PMID:18551021 PMID:23994555 PMID:28834606 | | ||||||||||||||||||||||
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