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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agt
Name: angiotensinogen
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtmultiple interactionsEXP 6480464CTDTretinoin inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; Tretinoin inhibits the reaction [AGT protein results in increased secretion of COL3A1 protein]PMID:16539842
Agtincreases expressionISOAgt (Mus musculus)6480464CTDTretinoin results in increased expression of AGT mRNAPMID:16505366
Agtmultiple interactionsISOAgt (Mus musculus)6480464CTDAGN 193109 inhibits the reaction [Tretinoin results in increased expression of AGT mRNA]PMID:16505366
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