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GENE - TERM ANNOTATION REPORT

RGD ID: 2065
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Afp
Name: alpha-fetoprotein
Acc ID: DOID:684
Term: hepatocellular carcinoma
Definition: A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver. (DO)
Definition Source(s): http://cancergenome.nih.gov/cancersselected/LiverHepatocellularCarcinoma "DO" "DO", http://en.wikipedia.org/wiki/Hepatocellular_carcinoma "DO" "DO", http://www.omim.org/entry/114550 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AfptreatmentIEP 152177911RGD  
Afp ISOAFP (Homo sapiens)125097525RGDprotein:increased expression:serum (human) 
Afpdisease_progressionISOAFP (Homo sapiens)126790579RGD  
Afpdisease_progressionISOAFP (Homo sapiens)126790583RGDassociated with hepatitis B 
AfpseverityISOAFP (Homo sapiens)14401581RGDprotein:increased expression:serum (human) 
Afp ISOAFP (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:9029167 PMID:15276417 PMID:24012840 PMID:28284560 PMID:32961231
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