GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Adrb2 | multiple interactions | EXP | | 6480464 | CTD | [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine; [ICI 118551 binds to and results in decreased activity of ADRB2 protein] inhibits the reaction [Fenoterol affects the abundance of Norepinephrine]; CGP 20712A inhibits the reaction [[Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine]; Fenoterol binds to and results in increased activity of ADRB2 protein | PMID:16474418 PMID:7969507 | Adrb2 | increases activity | ISO | ADRB2 (Homo sapiens) | 6480464 | CTD | Fenoterol results in increased activity of ADRB2 protein | PMID:34601065 | Adrb2 | increases phosphorylation | ISO | ADRB2 (Homo sapiens) | 6480464 | CTD | Fenoterol results in increased phosphorylation of ADRB2 protein | PMID:14722251 | Adrb2 | multiple interactions | ISO | ADRB2 (Homo sapiens) | 6480464 | CTD | [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased abundance of Potassium; [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; Fenoterol binds to and results in increased activity of ADRB2 protein; Fenoterol inhibits the reaction [cyanopindolol binds to ADRB2 protein]; ICI 118551 inhibits the reaction [Fenoterol results in increased activity of ADRB2 protein] | PMID:14730417 PMID:16980553 PMID:34601065 PMID:8102213 | |
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