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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1624095
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c39
Name: cytochrome P450, family 2, subfamily c, polypeptide 39
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c39decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CYP2C39 mRNAPMID:28123100
Cyp2c39multiple interactionsEXP 6480464CTD[bisphenol A co-treated with retinol acetate] results in increased expression of CYP2C39 mRNA; [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in decreased expression of CYP2C39 mRNAPMID:28123100
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