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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1619215 Species: Mus musculus RGD Object: Gene Symbol: Cyp3a41a Name: cytochrome P450, family 3, subfamily a, polypeptide 41A

Acc ID: CHEBI:3561 Term: cetirizine Definition: A monocarboxylic acid that has formula C21H25ClN2O3. CasRN: 83881-51-0 Chemical ID: MESH:D017332

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases activity	ISO	RGD:1352962	6480464	CTD	Cetirizine analog results in decreased activity of CYP3A4 protein Cetirizine results in decreased activity of CYP3A4 protein	PMID:15482930